Crisp October air has officially settled across the Mississippi River Valley, and St. Louis is kicking off the spooky season with an electric weekend lineup. Between national theater tours opening at Grand Center's historic venues, vibrant autumn neighborhood festivals spilling into city streets, and an array of late-night craft cocktail lounges and live music rooms, the Gateway City is humming with energy. Grab a light jacket, gather your favorite crew, and dive into your double-fact-checked weekend plan.
Friday, October 2
'Clue' Live on Stage
Day/Time: Friday, October 2 | 7:30 PM
Venue: The Fabulous Fox Theatre (Grand Center Arts District)
What to Expect: The hilarious whodunit murder mystery comedy takes over the historic Fox stage for its autumn run. Based on the iconic 1985 Paramount film and classic board game, this fast-paced national touring production promises slapstick comedy, mystery, and nostalga.
Link: Secure verified tickets directly through the Fabulous Fox Theatre.
St. Louis Symphony Orchestra: 'Debussy's La Mer'
Day/Time: Friday, October 2 | 7:30 PM
Venue: Powell Hall (Grand Center Arts District)
What to Expect: Conductor Stéphane Denève leads the SLSO through Debussy’s soaring orchestral masterpiece, La Mer, alongside evocative works by Sibelius and Berio inside Midtown's world-class acoustic hall.
Link: Reserve concert seats via SLSO.
Here Come The Mummies Live in Concert
Day/Time: Friday, October 2 | 8:00 PM
Venue: The Hawthorn (Downtown West)
What to Expect: The legendary eight-piece funk-rock band brings their high-energy, mummy-wrapped stage spectacle to Downtown West. Expect tight horn arrangements, unstoppable grooves, and pure showmanship.
Link: Get show details and tickets at The Hawthorn.
Maker Fest at MADE Makerspace
Day/Time: Friday, October 2 | 6:00 PM – 9:00 PM
Venue: MADE Makerspace (Delmar Divine / Academy)
What to Expect: Explore a massive 32,000-square-foot community workshop filled with live woodturning, screen-printing, 3D printing, and laser-cutting demonstrations. Chat directly with local artisans while enjoying food truck bites and neighborhood gathering vibes.
Link: Discover community workshops via MADE Makerspace.
Craft Cocktails & Historic Charms at Planter's House
Day/Time: Friday, October 2 | 4:00 PM – 12:00 AM
Venue: Planter's House (Lafayette Square)
What to Expect: Housed in an ornate 19th-century brick footprint overlooking Lafayette Square, this nationally acclaimed lounge serves house-made bitters, seasonal punch flights, and precision-mixed classics. Settle into a velvet booth for late-night spirits and elevated bar bites.
Link: View seasonal cocktail menus at Planter's House.
Eclectic Mosaics & Live Funk at Venice Cafe
Day/Time: Friday, October 2 | 4:00 PM – 1:00 AM (21+ after 8:00 PM)
Venue: Venice Cafe (Benton Park)
What to Expect: Step inside South City's iconic mosaic-tiled wonderland. Featuring multi-level courtyard nooks, eccentric local art, and live funk and blues acts on the indoor stage, it’s one of the city's most beloved nightcaps.
Link: Explore neighborhood spots through the Benton Park Neighborhood Association.
Saturday, October 3
Cherokee Street Brewed Arts Festival
Day/Time: Saturday, October 3 | 1:00 PM – 6:00 PM
Venue: Cherokee Street Historic District (Benton Park / Gravois Park)
What to Expect: Dozens of local breweries team up with independent galleries, print shops, and vintage storefronts along Cherokee Street. Stroll from shop to shop sampling regional craft beers while taking in live street art, acoustic sets, and pop-up markets.
Link: Find festival maps and participating venues on Cherokee Street.
Kirkwood Fall Fest
Day/Time: Saturday, October 3 | 12:00 PM – 10:00 PM
Venue: Downtown Kirkwood Plaza & Station
What to Expect: Historic Downtown Kirkwood comes alive with autumn celebrations featuring live regional music, artisan vendor booths, local food trucks, and seasonal craft beer gardens along the train tracks.
Link: Explore event schedules on the Downtown Kirkwood Directory.
Breakfast In America: A Supertramp Celebration
Day/Time: Saturday, October 3 | 8:00 PM
Venue: The Pageant (Delmar Loop)
What to Expect: Celebrate 70s progressive rock craftsmanship as top-tier tribute musicians perform Supertramp's iconic album in its entirety inside one of the finest listening rooms in the Midwest.
Link: Grab concert tickets via The Pageant.
Landmarks Downtown Walking Tour
Day/Time: Saturday, October 3 | 9:30 AM – 11:30 AM
Venue: St. Louis Public Library Central Library (Downtown)
What to Expect: Architectural historians lead an engaging walking tour through Downtown's rich historic cityscape, highlighting Gilded Age skyscrapers, terracotta ornamentation, and civic landmarks.
Link: Reserve tour spots through Landmarks Association of St. Louis.
Subterranean Jazz & Spirits at Thaxton Speakeasy
Day/Time: Saturday, October 3 | 9:00 PM – 2:00 AM (21+)
Venue: Thaxton Speakeasy (Downtown)
What to Expect: Knock on the alley door of this subterranean Art Deco lounge for prohibition-era cocktail recipes, vintage jazz spins, and an atmospheric midnight lounge experience beneath the city streets.
Link: Request the weekly entry password via Thaxton Speakeasy.
Retro Arcade Games & Craft Taps at Up-Down STL
Day/Time: Saturday, October 3 | 11:00 AM – 1:30 AM (21+ after 8:00 PM)
Venue: Up-Down STL (Central West End)
What to Expect: Over 50 classic 80s and 90s arcade cabinets, pinball machines, and skee-ball lanes paired with a massive bi-level outdoor patio, extensive regional craft beer taps, and pizza by the slice.
Link: Browse the arcade floor plan on the Central West End Scene.
High-Energy Spirits & Outdoor Dining at Sub Zero Vodka Bar
Day/Time: Saturday, October 3 | 5:00 PM – 1:30 AM (21+)
Venue: Sub Zero Vodka Bar (Central West End)
What to Expect: Sip curated martini flights or craft pours from an extensive vodka library while enjoying gourmet sushi rolls and energetic street-side patio seating along Euclid Avenue.
Link: View food and drink menus on CWE Scene.
Sunday, October 4
Buzzcocks Live in Concert
Day/Time: Sunday, October 4 | 8:00 PM
Venue: Delmar Hall (Delmar Loop)
What to Expect: Legendary UK punk pioneers bring their enduring energy and iconic catalog to Delmar Hall for an intimate, high-octane Sunday night performance.
Link: Reserve concert seats via Delmar Hall.
Amy Bruni Live: Ghosthunter Stories & Intimate Performance
Day/Time: Sunday, October 4 | 7:30 PM
Venue: City Winery at City Foundry STL (Midtown)
What to Expect: Paranormal researcher, author, and TV personality Amy Bruni takes the stage for a captivating evening of real-world storytelling, ghost-hunting lore, and Q&A inside City Winery's intimate performance hall.
Link: Reserve table seating via City Winery St. Louis.
JJ Grey & Mofro Live in Concert
Day/Time: Sunday, October 4 | 7:30 PM
Venue: Atomic Pavilion (Downtown West)
What to Expect: Southern soul, funk, and blues-rock take center stage as JJ Grey brings his gravelly vocals and infectious stage presence to Downtown West for an unforgettable weekend capstone.
Link: Find concert details through Atomic Pavilion STL.
Sunday Gallery Walk at Contemporary Art Museum STL
Day/Time: Sunday, October 4 | 11:00 AM – 5:00 PM
Venue: Contemporary Art Museum St. Louis (Grand Center Arts District)
What to Expect: Experience cutting-edge autumn exhibitions inside CAM’s light-filled, open-concept gallery space with free admission all afternoon. Enjoy quiet art walks and courtyard reflection.
Link: Explore current exhibitions at CAM STL.
Session Ales & Courtyard Gathering at Civil Life Brewing Co.
Day/Time: Sunday, October 4 | 12:00 PM – 9:00 PM (21+)
Venue: Civil Life Brewing Co. (Tower Grove South)
What to Expect: Unwind on Sunday evening inside one of South City's most welcoming pub courtyards. Famous for sessionable English-style ales, house-baked soft pretzels, and a cozy community living-room atmosphere.
Link: Check current tap lists on The Civil Life.
Single-Barrel Whiskeys & Scratch Pastas at Small Batch
Day/Time: Sunday, October 4 | 4:00 PM – 10:00 PM
Venue: Small Batch Whiskey & Fare (Midtown)
What to Expect: Set inside a restored 1920s Ford auto showroom, this plant-forward lounge offers curated tasting flights of rare single-barrel whiskies, craft cocktails, and scratch-made pastas.
Link: View dinner and whiskey menus via Small Batch STL.
Local Lens Spotlight: Sophie's Artist Lounge
3333 Washington Ave, St. Louis, MO 63103 (Grand Center Arts District)
Tucked on the second floor of the Kranzberg Arts Foundation building, Sophie's Artist Lounge is a sleek, art-forward cocktail lounge designed specifically as a gathering hub for local creators and patrons. Featuring floor-to-ceiling murals, plush lounge seating, rotating DJ vinyl sets, and craft cocktails, it’s the ultimate Midtown spot to recap the night after a show at The Fox, Powell Hall, or Delmar Hall.